Chitinase-3-Like Protein 1 (CHI3L1) Antibody

CHI3L1 Antibody is a Rabbit Polyclonal antibody against CHI3L1. Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling. [provided by RefSeq, Sep 2009].

Target	Chitinase-3-Like Protein 1 (CHI3L1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 22-220 of human YKL-40/CHI3L1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P36222 (UniProt, ExPASy)
UniProt Secondary AC	B2R7B0, P30923, Q8IVA4, Q96HI7
UniProt Entry Name	CH3L1_HUMAN
Gene Symbol	CHI3L1
GeneID	1116
OMIM	181500
NCBI Accession	NP_001267.2
HGNC	1932
KEGG	hsa:1116
Ensembl	ENSG00000133048
String	9606.ENSP00000255409
Molecular Weight	Calculated MW: 43 kDa Observed MW: 30-45 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	1.55 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Chitinase-3-Like Protein 1 (CHI3L1)

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