Charged Multivesicular Body Protein 5 (CHMP5) Antibody
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Catalogue No: abx030388
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US$326.25
(Size: 80 µl)
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Datasheet SDS
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
Research Articles on Charged Multivesicular Body Protein 5 (CHMP5)
| Target | Charged Multivesicular Body Protein 5 (CHMP5) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 178-204 amino acids from the C-terminal region of human CHMP5. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9NZZ3 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RD95, B4DIR6, Q5VXW2, Q96AV2, Q9HB68, Q9NYS4, Q9Y323 |
| UniProt Entry Name | CHMP5_HUMAN |
| Gene Symbol | CHMP5 |
| String | 9606.ENSP00000223500 |
| Molecular Weight | Calculated MW: 24.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat CHMP5. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |