Muscarinic Acetylcholine Receptor M1 (CHRM1) Antibody

CHRM1 Antibody is a Rabbit Polyclonal antibody against CHRM1. The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008].

Target	Muscarinic Acetylcholine Receptor M1 (CHRM1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 251-350 of human CHRM1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P11229 (UniProt, ExPASy)
UniProt Secondary AC	Q96RH1
UniProt Entry Name	ACM1_HUMAN
Gene Symbol	CHRM1
GeneID	1128
NCBI Accession	NP_000729.2
KEGG	hsa:1128
String	9606.ENSP00000306490
Molecular Weight	Calculated MW: 51 kDa Observed MW: 51 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Muscarinic Acetylcholine Receptor M1 (CHRM1)

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