Muscarinic Acetylcholine Receptor M5 (CHRM5) Antibody

CHRM5 Antibody is a Rabbit Polyclonal antibody against CHRM5. The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels.

Target	Muscarinic Acetylcholine Receptor M5 (CHRM5)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 275-370 of human CHRM5.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P08912 (UniProt, ExPASy)
UniProt Secondary AC	Q96RG7
UniProt Entry Name	ACM5_HUMAN
Gene Symbol	CHRM5
GeneID	1133
NCBI Accession	NP_036257.1
KEGG	hsa:1133
String	9606.ENSP00000372750
Molecular Weight	Calculated MW: 60 kDa Observed MW: 60 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	1.09 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Muscarinic Acetylcholine Receptor M5 (CHRM5)

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