Cholinergic Receptor, Nicotinic Beta 1 (CHRNB1) Antibody

CHRNB1 Antibody is a Rabbit Polyclonal antibody against CHRNB1. The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

Target	Cholinergic Receptor, Nicotinic Beta 1 (CHRNB1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 25-235 of human CHRNB1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P11230 (UniProt, ExPASy)
UniProt Secondary AC	B7Z5H1, Q8IZ46, Q96FB8
UniProt Entry Name	ACHB_HUMAN
Gene Symbol	CHRNB1
GeneID	1140
NCBI Accession	NP_000738.2
KEGG	hsa:1140
String	9606.ENSP00000304290
Molecular Weight	Calculated MW: 57 kDa Observed MW: 63 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cholinergic Receptor, Nicotinic Beta 1 (CHRNB1)

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