Cytokine Inducible SH2 Containing Protein (CISH) Antibody
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Catalogue No: abx004804
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US$348.00
(Size: 60 µl)
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Datasheet SDS
CISH Antibody is a Rabbit Polyclonal antibody against CISH. The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Articles on Cytokine Inducible SH2 Containing Protein (CISH)
| Target | Cytokine Inducible SH2 Containing Protein (CISH) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human CISH |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9NSE2 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R9N1, G5E9R1, Q9NS38, Q9Y5R1 |
| UniProt Entry Name | CISH_HUMAN |
| Gene Symbol | CISH |
| GeneID | 1154 |
| NCBI Accession | NP_659508.1 |
| String | 9606.ENSP00000409346 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
