Claudin 5 (CLDN5) Antibody

Claudin 5 (CLDN5) Antibody is a Rabbit Polyclonal antibody for the detection of CLDN5.

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Target	Claudin 5 (CLDN5)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	CLDN5
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	O00501 (UniProt, ExPASy)
UniProt Secondary AC	B3KS11, Q53XW2, Q8WUW3
UniProt Entry Name	CLD5_HUMAN
Gene Symbol	CLDN5
GeneID	7122
OMIM	602101
HGNC	2047
KEGG	hsa:7122
Ensembl	ENSG00000184113
String	9606.ENSP00000385477
Molecular Weight	Observed MW: 25 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Claudin 5 (CLDN5)

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