Claudin 2 (CLDN2) Antibody

CLDN2 Antibody is a Rabbit Polyclonal antibody against CLDN2. This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.

Target	Claudin 2 (CLDN2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 30-230 of human CLDN2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P57739 (UniProt, ExPASy)
UniProt Secondary AC	B2R6B9
UniProt Entry Name	CLD2_HUMAN
Gene Symbol	CLDN2
GeneID	9075
NCBI Accession	NP_001164566.1
KEGG	hsa:9075
String	9606.ENSP00000441283
Molecular Weight	Calculated MW: 25 kDa Observed MW: 20 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Claudin 2 (CLDN2)

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