Claudin 3 (CLDN3) Antibody

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Catalogue No: abx002148
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
CLDN3 Antibody is a Rabbit Polyclonal antibody against CLDN3. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

Target Claudin 3 (CLDN3)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 141-220 of human CLDN3.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O15551 (UniProt, ExPASy)
UniProt Entry Name CLD3_HUMAN
Gene Symbol CLDN3
GeneID 1365
NCBI Accession NP_001297.1
KEGG hsa:1365
String 9606.ENSP00000378577
Molecular Weight Calculated MW: 23 kDa
Observed MW: 20 kDa
Buffer PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Claudin 3 (CLDN3)


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