Claudin 7 (CLDN7) Antibody

CLDN7 Antibody is a Rabbit Polyclonal antibody against CLDN7. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010].

Target	Claudin 7 (CLDN7)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/5000, IF/ICC: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 29-211 of human CLDN7.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O95471 (UniProt, ExPASy)
UniProt Secondary AC	B2R9X7, D3DTP0, Q6IPN3, Q7Z4Y7, Q9BVN0
UniProt Entry Name	CLD7_HUMAN
Gene Symbol	CLDN7
GeneID	1366
NCBI Accession	NP_001298.3
KEGG	hsa:1366
String	9606.ENSP00000353475
Molecular Weight	Calculated MW: 22 kDa Observed MW: 22 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Claudin 7 (CLDN7)

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