+44 (0) 1223 755950
+1 832 327 7413
Circadian Locomotor Output Cycles Protein Kaput (CLOCK) Cell ELISA Kit
REQUEST MORE INFO
Catalogue No: abx595660
Price:
US$572.75
(Size: 96 tests)
Orders to United States ship from United States
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Add to Shopping Cart
Buy It Now
GET A QUOTE
Clock Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear flat bottom 96 well plate, using poly-L-lysine for non-adherent cells. Cells should be grown to 75-90% confluence and treated prior to carrying out the ELISA.
Research Articles on CLOCK
| Introduction | Circadian Locomotor Output Cycles Protein Kaput (CLOCK) is a transcription factor involved in circadian rhythm. Based off studies on mice and fruit flies, CLOCK can dimerise with BMAL1 and bind to E-box elements in DNA to increase mRNA for PER proteins, thereby increasing those proteins’ expression. Mutations in CLOCK are associated with increased circadian cycles, sympathetic behaviour, insomnia, depression, and metabolic disorders. |
| Target | CLOCK |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Validity | 6 months. |
| UniProt Primary AC | O15516 (UniProt, ExPASy) |
| UniProt Secondary AC | A0AV01, A2I2N9, O14516, Q9UIT8 |
| UniProt Entry Name | CLOCK_HUMAN |
| Gene Symbol | CLOCK |
| GeneID | 9575 |
| OMIM | 601851 |
| HGNC | 2082 |
| KEGG | hsa:9575 |
| Ensembl | ENSG00000134852 |
| String | 9606.ENSP00000308741 |
| Detection Method | Colorimetric |
| Plate Coating | Uncoated |
| Substrate | TMB |
| Detection Antibody Conjugation | HRP |
| Availability | Shipped within 1-2 weeks. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |