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Ciliary Neurotrophic Factor (CNTF) Antibody

Catalogue No: abx001565
Price: £120.00
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Ciliary Neurotrophic Factor (CNTF) Antibody

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CNTF Antibody is a Rabbit Polyclonal antibody against CNTF. The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.

Target CNTF
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CNTF.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P26441 (UniProt, ExPASy)
UniProt Secondary AC B2RAB2
UniProt Entry Name CNTF_HUMAN
Gene Symbol CNTF
GeneID 1270
KEGG hsa:1270
String 9606.ENSP00000355370
Molecular Weight Calculated MW: 22 kDa
Observed MW: 26 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Ciliary Neurotrophic Factor (CNTF) Antibody

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