Ciliary Neurotrophic Factor Receptor Subunit Alpha (CNTFR) Antibody

CNTFR Antibody is a Rabbit Polyclonal antibody against CNTFR. This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.

Target	Ciliary Neurotrophic Factor Receptor Subunit Alpha (CNTFR)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/400 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 90-342 of human CNTFR.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P26992 (UniProt, ExPASy)
UniProt Secondary AC	Q5U050
UniProt Entry Name	CNTFR_HUMAN
Gene Symbol	CNTFR
GeneID	1271
NCBI Accession	NP_671693.1
KEGG	hsa:1271
String	9606.ENSP00000368265
Molecular Weight	Calculated MW: 41 kDa Observed MW: 41 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ciliary Neurotrophic Factor Receptor Subunit Alpha (CNTFR)

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