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Collagen Type XVIII Alpha 1 (COL18A1) Antibody

Catalogue No: abx001439
Price: £120.00
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Collagen Type XVIII Alpha 1 (COL18A1) Antibody

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COL18A1 Antibody is a Rabbit Polyclonal antibody against COL18A1. This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].

Target Collagen Type XVIII alpha 1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human COL18A1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P39060 (UniProt, ExPASy)
UniProt Entry Name COIA1_HUMAN
Gene Symbol COL18A1
GeneID 80781
KEGG hsa:80781
String 9606.ENSP00000347665
Molecular Weight Calculated MW: 135 kDa, 154 kDa, 178 kDa
Observed MW: 240 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Collagen Type XVIII Alpha 1 (COL18A1) Antibody

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