Collagen Type II Alpha 1 (COL2A1) Antibody

Catalogue No: abx001311
Price: £120.00
(Size: 20 µl)
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COL2A1 Antibody is a Rabbit Polyclonal antibody against COL2A1. This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.

Target Collagen Type II alpha 1
Clonality Polyclonal
Reactivity Human, Mouse,
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human COL2A1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P02458 (UniProt, ExPASy)
Gene Symbol COL2A1
GeneID 1280
Molecular Weight Calculated MW: 29 kDa, 134 kDa, 141 kDa
Observed MW: 100 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Collagen Type II alpha 1

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