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Complement C3 (C3) Antibody (Biotin)

Catalogue No: abx105281
Price: £130.00
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Complement C3 (C3) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Complement C3. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Target Complement C3 (C3)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA
Host Rabbit
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Conjugation Biotin
Immunogen Recombinant human Complement C3 protein (26-225AA).
Isotype IgG
Form Liquid
Purity > 95%
Purification Protein G.
Storage Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01024 (UniProt, ExPASy)
UniProt Secondary AC A7E236
UniProt Entry Name CO3_HUMAN
Gene Symbol C3
GeneID 718
OMIM 120700
HGNC 1318
KEGG hsa:718
Ensembl ENSG00000125730
String 9606.ENSP00000245907
Buffer 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Complement C3 (C3) Antibody (Biotin)

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