Gap Junction Alpha-1 Protein / CX43 (GJA1) Antibody

Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. Connexin 43 is targeted by several protein kinases that regulate myocardial cell-cell coupling. A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5.

Target	Gap Junction Alpha-1 Protein / CX43 (GJA1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 107-138 amino acids from the N-terminal region of human Connexin 43.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P17302 (UniProt, ExPASy)
UniProt Secondary AC	B2R5U9, Q6FHU1, Q9Y5I8
UniProt Entry Name	CXA1_HUMAN
NCBI Accession	NP_000156.1
KEGG	hsa:2697
String	9606.ENSP00000282561
Molecular Weight	Calculated MW: 43 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow and Xenopus GJA1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Gap Junction Alpha-1 Protein / CX43 (GJA1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue