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COP9 Signalosome Subunit 5 (COPS5) Antibody

Catalogue No: abx001465
Price: £120.00
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COP9 Signalosome Subunit 5 (COPS5) Antibody COP9 Signalosome Subunit 5 (COPS5) Antibody COP9 Signalosome Subunit 5 (COPS5) Antibody COP9 Signalosome Subunit 5 (COPS5) Antibody

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COPS5 Antibody is a Rabbit Polyclonal antibody against COPS5. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors.

Target COP9 Signalosome Subunit 5 (COPS5)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human COPS5 (NP_006828.2).
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q92905 (UniProt, ExPASy)
UniProt Secondary AC O15386, Q6AW95, Q86WQ4, Q9BQ17
UniProt Entry Name CSN5_HUMAN
Gene Symbol COPS5
GeneID 10987
KEGG hsa:10987
String 9606.ENSP00000350512
Molecular Weight Calculated MW: 37 kDa
Observed MW: 37 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 2.62 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on COP9 Signalosome Subunit 5 (COPS5) Antibody

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