Coactosin-Like Protein (COTL1) Antibody

This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton.This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis.Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16.The Smith-Magenis syndrome region is the site of two related pseudogenes.

Target	Coactosin-Like Protein (COTL1)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human COTL1 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q14019 (UniProt, ExPASy)
UniProt Secondary AC	B2RDU3, D3DUL9, Q86XM5
UniProt Entry Name	COTL1_HUMAN
Gene Symbol	COTL1
GeneID	23406
OMIM	606748
HGNC	18304
KEGG	hsa:23406
Ensembl	ENSG00000103187
String	9606.ENSP00000262428
Molecular Weight	16 kDa
Buffer	PBS, containing 0.05% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Coactosin-Like Protein (COTL1)

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