SARS-CoV-2 Nucleocapsid Protein

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Nucleocapsid Protein (NP) is a recombinant protein expressed in HEK293 cells.

The SARS-CoV-2 Nucleoprotein (also known as Nucleocapsid Protein or N Protein) is a protein that binds to the RNA in the viral particle. Changes to two amino acids in the nucleoprotein are thought to contribute to the virus’ ability to infect humans; this mutation allows the virus to reduce the binding capability of an HLA-C allele found in many Europeans. The nucleoprotein is the second most-common protein in SARS-CoV-2 targeted by the immune system, after the spike protein.

Target	Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Nucleocapsid Protein
Origin	Virus
Expression	Recombinant
Tested Applications	ELISA, WB, LF
Host	HEK293 cells
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Form	Liquid
Purity	≥ 90% (SDS-PAGE)
Purification	Purified by affinity chromatography.
Storage	Store unopened at -80 °C. Working aliquots can be prepared and stored at or below -20 °C for up to 3 months. Avoid repeated freeze/thaw cycles.
Sequence	Full length.
Tag	DYKDDDDK tag.
Buffer	0.1 M glycine, 50 mM Tris chloride, 150 mM sodium chloride, pH 7.4. Does not contain preservatives.
Availability	Shipped within 10-20 working days.
Note	This product is for research use only. This product is shipped with dry ice.
Directions for use	Centrifuge before opening to ensure complete recovery of vial contents.

Research Articles on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Nucleocapsid Protein

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