Cytochrome C Oxidase Subunit 4I1 (COX4I1) Antibody

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.

Target	Cytochrome C Oxidase Subunit 4I1 (COX4I1)
Clonality	Monoclonal
Reactivity	Human, Monkey, Rat, Mouse
Tested Applications	ELISA, WB, IF/ICC, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human COX4I1 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P13073 (UniProt, ExPASy)
UniProt Secondary AC	B2R4J2, D3DUM7, Q6P666
UniProt Entry Name	COX41_HUMAN
GeneID	1327
KEGG	hsa:1327
String	9606.ENSP00000457513
Enzyme Commission Number	EC 1.9.3.1
Molecular Weight	19 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cytochrome C Oxidase Subunit 4I1 (COX4I1)

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