Cytochrome C Oxidase Subunit 6A1 (COX6A1) Antibody

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Catalogue No: abx002749
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
COX6A1 Antibody is a Rabbit Polyclonal antibody against COX6A1. Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented.

Target Cytochrome C Oxidase Subunit 6A1 (COX6A1)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/200 - 1/2000, IHC-P: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 25-109 of human COX6A1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P12074 (UniProt, ExPASy)
UniProt Secondary AC B2R500, O43714, Q32Q37
UniProt Entry Name CX6A1_HUMAN
Gene Symbol COX6A1
GeneID 1337
NCBI Accession NP_004364.2
KEGG hsa:1337
String 9606.ENSP00000229379
Molecular Weight Calculated MW: 12 kDa
Observed MW: 12 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Cytochrome C Oxidase Subunit 6A1 (COX6A1)


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