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Phospholipase A2, Cytosolic (cPLA2) Antibody

Catalogue No: abx000706
Price: £120.00
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cPLA2 Antibody is a Rabbit Polyclonal antibody against cPLA2. This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.

Target cPLA2
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/200 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human cPLA2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P47712 (UniProt, ExPASy)
UniProt Secondary AC B1AKG4, Q29R80
UniProt Entry Name PA24A_HUMAN
Gene Symbol PLA2G4A
GeneID 5321
String 9606.ENSP00000356436
Molecular Weight Calculated MW: 85 kDa
Observed MW: 115 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Phospholipase A2, Cytosolic (cPLA2) Antibody

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