CASP2 And RIPK1 Domain Containing Adaptor With Death Domain (CRADD) Antibody

CRADD Antibody is a Rabbit Polyclonal antibody against CRADD. The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. [provided by RefSeq, Jul 2008].

Target	CASP2 And RIPK1 Domain Containing Adaptor With Death Domain (CRADD)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human RAIDD/RAIDD/CRADD.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P78560 (UniProt, ExPASy)
UniProt Secondary AC	B7Z2Q5
UniProt Entry Name	CRADD_HUMAN
Gene Symbol	CRADD
GeneID	8738
NCBI Accession	NP_003796.1
KEGG	hsa:8738
String	9606.ENSP00000439068
Molecular Weight	Calculated MW: 23 kDa Observed MW: 22 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on CASP2 And RIPK1 Domain Containing Adaptor With Death Domain (CRADD)

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