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Cryptochrome 2 (CRY2) Antibody
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Catalogue No: abx005245
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
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CRY2 Antibody is a Rabbit Polyclonal antibody against CRY2. This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on Cryptochrome 2 (CRY2)
| Target | Cryptochrome 2 (CRY2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human CRY2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q49AN0 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DH32, B4DZD6, O75148, Q8IV71 |
| UniProt Entry Name | CRY2_HUMAN |
| Gene Symbol | CRY2 |
| GeneID | 1408 |
| NCBI Accession | NP_066940.3 |
| KEGG | hsa:1408 |
| String | 9606.ENSP00000478187 |
| Molecular Weight | Calculated MW: 60 kDa/66 kDa Observed MW: 70 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
