Cryptochrome 2 (CRY2) Antibody

CRY2 Antibody is a Rabbit Polyclonal antibody against CRY2. This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene.

Target	Cryptochrome 2 (CRY2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human CRY2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q49AN0 (UniProt, ExPASy)
UniProt Secondary AC	B4DH32, B4DZD6, O75148, Q8IV71
UniProt Entry Name	CRY2_HUMAN
Gene Symbol	CRY2
GeneID	1408
NCBI Accession	NP_066940.3
KEGG	hsa:1408
String	9606.ENSP00000478187
Molecular Weight	Calculated MW: 67 kDa Observed MW: 67 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cryptochrome 2 (CRY2)

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