Ketimine Reductase Mu-Crystallin (CRYM) Antibody

CRYM Antibody is a Rabbit Polyclonal antibody against CRYM. Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene.

Target	Ketimine Reductase Mu-Crystallin (CRYM)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-314 of human CRYM.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q14894 (UniProt, ExPASy)
UniProt Secondary AC	D5MNX0, Q5HYB7
UniProt Entry Name	CRYM_HUMAN
Gene Symbol	CRYM
GeneID	1428
NCBI Accession	NP_001879.1
KEGG	hsa:1428
String	9606.ENSP00000219599
Molecular Weight	Calculated MW: 34 kDa Observed MW: 36 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ketimine Reductase Mu-Crystallin (CRYM)

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