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Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) Antibody

Catalogue No: abx002189
Price: £120.00
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Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) Antibody

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CSF1R Antibody is a Rabbit Polyclonal antibody against CSF1R. The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.

Target CSF1R
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human CSF1R.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P07333 (UniProt, ExPASy)
UniProt Secondary AC B5A955, D3DQG2, Q6LDW5, Q6LDY4, Q86VW7
UniProt Entry Name CSF1R_HUMAN
Gene Symbol CSF1R
GeneID 1436
KEGG hsa:1436
String 9606.ENSP00000286301
Molecular Weight Calculated MW: 33 kDa, 107 kDa
Observed MW: 117 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) Antibody

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