Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) Antibody

CSF1R Antibody is a Rabbit Polyclonal antibody against CSF1R. The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.

Target	Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 873-972 of human CD115/CSF-1R.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P07333 (UniProt, ExPASy)
UniProt Secondary AC	B5A955, D3DQG2, Q6LDW5, Q6LDY4, Q86VW7
UniProt Entry Name	CSF1R_HUMAN
Gene Symbol	CSF1R
GeneID	1436
NCBI Accession	NP_005202.2
KEGG	hsa:1436
String	9606.ENSP00000286301
Molecular Weight	Calculated MW: 108 kDa Observed MW: 150-190 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R)

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