Casein Kinase I Isoform Alpha (CSNK1A1) Antibody
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Catalogue No: abx033375
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CK1a can phosphorylate a large number of proteins. This cytoplasmic protein participates in Wnt signaling. It has been demonstrated to phosphorylate CTNNB1 on Ser-45 and to interact with the Axin complex.
Research Articles on Casein Kinase I Isoform Alpha (CSNK1A1)
| Target | Casein Kinase I Isoform Alpha (CSNK1A1) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 309-337 amino acids from the C-terminal region of human CSNK1A1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P48729 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DQG0, D3DQG1, Q4JJA0, Q5U046, Q5U047, Q6FGA2, Q71TU5, Q96HD2, Q9UDK3 |
| UniProt Entry Name | KC1A_HUMAN |
| Gene Symbol | CSNK1A1 |
| GeneID | 1452 |
| OMIM | 600505 |
| HGNC | 2451 |
| KEGG | hsa:1452 |
| Ensembl | ENSG00000113712 |
| Enzyme Commission Number | EC 2.7.11.1 |
| Molecular Weight | Calculated MW: 38.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Chicken and Xenopus CSNK1A1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |