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Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4) Antibody

Catalogue No: abx001680
Price: £120.00
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Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4) Antibody

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CTLA4 Antibody is a Rabbit Polyclonal antibody against CTLA4. This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008].

Target Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human AKT1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P16410 (UniProt, ExPASy)
UniProt Entry Name CTLA4_HUMAN
Gene Symbol CTLA4
GeneID 1493
KEGG hsa:1493
String 9606.ENSP00000303939
Molecular Weight Calculated MW: 6 kDa, 8 kDa, 19 kDa, 24 kDa
Observed MW: 33 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4) Antibody

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