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CTNNB1 (pY333) Antibody

Catalogue No: abx000385
Price: £230.00
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CTNNB1 (pY333) Antibody

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CTNNB1 (pY333) Antibody is a Rabbit Polyclonal antibody against CTNNB1 (pY333). The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (pYR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.

Target CTNNB1 (pY333)
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y333 of human CTNNB1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P35222 (UniProt, ExPASy)
UniProt Secondary AC A8K1L7, Q8NEW9, Q8NI94, Q9H391
Gene Symbol CTNNB1
GeneID 1499
Molecular Weight Calculated MW: 9 kDa, 85 kDa
Observed MW: 85 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on CTNNB1 (pY333) Antibody

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