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Cathepsin B (CTSB) Antibody

Catalogue No: abx000920
Price: £120.00
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Cathepsin B (CTSB) Antibody

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CTSB Antibody is a Rabbit Polyclonal antibody against CTSB. The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.

Target Cathepsin B (CTSB)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CTSB.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P07858 (UniProt, ExPASy)
UniProt Secondary AC B3KQR5, B3KRR5, Q503A6, Q96D87
UniProt Entry Name CATB_HUMAN
Gene Symbol CTSB
GeneID 1508
KEGG hsa:1508
String 9606.ENSP00000345672
Molecular Weight Calculated MW: 37 kDa
Observed MW: 42 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Cathepsin B (CTSB) Antibody

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