Cathepsin F (CTSF) Antibody
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Price:
US$326.25
(Size: 80 µl)
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Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF is a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway.
Target |
Cathepsin F (CTSF) |
Clonality |
Polyclonal |
Reactivity |
Human |
Tested Applications |
ELISA, WB, IHC, FCM |
Host |
Rabbit |
Recommended dilutions |
WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation |
Unconjugated |
Immunogen |
KLH-conjugated synthetic peptide between 261-290 amino acids from the Central region of human CTSF. |
Isotype |
IgG |
Form |
Liquid |
Purification |
Purified Rabbit Polyclonal Antibody. |
Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
UniProt Primary AC |
Q9UBX1 (UniProt,
ExPASy)
|
UniProt Secondary AC |
B2R964, O95240, Q9NSU4, Q9UKQ5 |
UniProt Entry Name |
CATF_HUMAN |
String |
9606.ENSP00000310832
|
Molecular Weight |
Calculated MW: 53.4 kDa |
Buffer |
PBS containing 0.09% sodium azide. |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |
Research Articles on Cathepsin F (CTSF)