Cullin 3 (CUL3) Antibody

Cullin 3 Antibody is a Rabbit Polyclonal antibody against Cullin 3. This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Target	Cullin 3 (CUL3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 468-768 of human Cullin 3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13618 (UniProt, ExPASy)
UniProt Secondary AC	A8K536, B8ZZC3, O75415, Q569L3, Q9UBI8, Q9UET7
UniProt Entry Name	CUL3_HUMAN
Gene Symbol	CUL3
GeneID	8452
NCBI Accession	NP_003581.1
KEGG	hsa:8452
String	9606.ENSP00000264414
Molecular Weight	Calculated MW: 89 kDa Observed MW: 84 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cullin 3 (CUL3)

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