Growth-Regulated Alpha Protein / GROA (CXCL1) Antibody

CXCL1 Antibody is a Rabbit Polyclonal antibody against CXCL1. This gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.

Target	Growth-Regulated Alpha Protein / GROA (CXCL1)
Clonality	Polyclonal
Reactivity	Human, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1-107 of human GRO alpha.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P09341 (UniProt, ExPASy)
UniProt Secondary AC	Q9UCR7
UniProt Entry Name	GROA_HUMAN
Gene Symbol	CXCL1
GeneID	2919
NCBI Accession	NP_001502.1
KEGG	hsa:2919
String	9606.ENSP00000379110
Molecular Weight	Calculated MW: 11 kDa Observed MW: 11 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	2.13 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Growth-Regulated Alpha Protein / GROA (CXCL1)

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