Chemokine C-X-C-Motif Receptor 3 (CXCR3) Antibody

Catalogue No: abx002145
Price: £120.00
(Size: 20 µl)
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CXCR3 Antibody is a Rabbit Polyclonal antibody against CXCR3. The neuronal growth-associated protein GAP43 is also known as neuromodulin, B-50, P-57, F1 and pp46. Deficiency of GAP43 in mice results in death early in the postnatal period. GAP43 is one of the main substrates for protein kinase C in the brain. GAP43 is an intracellular growth-associated protein that appears to assist neuronal pathfinding and branching during development and regeneration, and may contribute to presynaptic membrane changes in the adult, leading to the neurotransmitter release, endocytosis and synaptic vesicle recycling, long-term potentiation, spatial memory formation, and learning. The predicated molecular weight of about 25 kDa is much lower than the apparent observed molecular weight of 43 kDa on SDS-PAGE gels, and this occurs because the highly charged nature of GAP43 causes it to bind less than the average amount of SDS per amino acid, and because the protein has an elongated structure.

Target Chemokine C-X-C-Motif Receptor 3 (CXCR3)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human CXCR3.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P49682 (UniProt, ExPASy)
UniProt Secondary AC B2R982, O15185, Q7Z710, Q9P2T4, Q9P2T5
UniProt Entry Name CXCR3_HUMAN
Gene Symbol CXCR3
GeneID 2833
KEGG hsa:2833
String 9606.ENSP00000362795
Molecular Weight Calculated MW: 28 kDa, 40 kDa, 45 kDa
Observed MW: 44 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Chemokine C-X-C-Motif Receptor 3 (CXCR3)

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