Chemokine C-X-C-Motif Receptor 4 (CXCR4) Antibody

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].

Target	Chemokine C-X-C-Motif Receptor 4 (CXCR4)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human CXCR4.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P61073 (UniProt, ExPASy)
UniProt Secondary AC	B2R5N0, O60835, P30991, P56438, Q53S69, Q9BXA0, Q9UKN2
UniProt Entry Name	CXCR4_HUMAN
KEGG	hsa:7852
String	9606.ENSP00000386884
Molecular Weight	Calculated MW: 39.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat, Cow, Pig, Sheep and Monkey CXCR4.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Chemokine C-X-C-Motif Receptor 4 (CXCR4)

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