Chemokine C-X-C-Motif Receptor 4 (CXCR4) Antibody
REQUEST MORE INFO
Catalogue No: abx000047
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
(
Click on the image to see the image legend
Add to Cart
Buy It Now
GET A QUOTE
Documents
Datasheet SDS
CXCR4 Antibody is a Rabbit Polyclonal antibody against CXCR4. This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
Research Articles on Chemokine C-X-C-Motif Receptor 4 (CXCR4)
| Target | Chemokine C-X-C-Motif Receptor 4 (CXCR4) |
| Research Area | Signal Transduction, Cellular Differentiation and Adhesion, Tumor Immunity, Infection Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human CXCR4 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P61073 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R5N0, O60835, P30991, P56438, Q53S69, Q9BXA0, Q9UKN2 |
| UniProt Entry Name | CXCR4_HUMAN |
| Gene Symbol | CXCR4 |
| GeneID | 7852 |
| NCBI Accession | NP_003458.1 |
| KEGG | hsa:7852 |
| String | 9606.ENSP00000386884 |
| Molecular Weight | Calculated MW: 39 kDa/40 kDa Observed MW: 36 kDa/70 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
