Chemokine C-X-C-Motif Receptor 4 (CXCR4) Antibody

CXCR4 Antibody is a Rabbit Polyclonal antibody against CXCR4. This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

Target	Chemokine C-X-C-Motif Receptor 4 (CXCR4)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CXCR4.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P61073 (UniProt, ExPASy)
UniProt Secondary AC	B2R5N0, O60835, P30991, P56438, Q53S69, Q9BXA0, Q9UKN2
UniProt Entry Name	CXCR4_HUMAN
Gene Symbol	CXCR4
GeneID	7852
NCBI Accession	NP_003458.1
KEGG	hsa:7852
String	9606.ENSP00000386884
Molecular Weight	Calculated MW: 40 kDa Observed MW: 36/70 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Chemokine C-X-C-Motif Receptor 4 (CXCR4)

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