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Cytochrome B-245 Heavy Chain (CYBB) Antibody

Catalogue No: abx001378
Price: £120.00
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Cytochrome B-245 Heavy Chain (CYBB) Antibody Cytochrome B-245 Heavy Chain (CYBB) Antibody Cytochrome B-245 Heavy Chain (CYBB) Antibody Cytochrome B-245 Heavy Chain (CYBB) Antibody Cytochrome B-245 Heavy Chain (CYBB) Antibody

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CYBB Antibody is a Rabbit Polyclonal antibody against CYBB. Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008].

Target CYBB
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CYBB.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P04839 (UniProt, ExPASy)
UniProt Secondary AC A8K138, Q2PP16
UniProt Entry Name CY24B_HUMAN
Gene Symbol CYBB
GeneID 1536
KEGG hsa:1536
String 9606.ENSP00000367851
Molecular Weight Calculated MW: 65 kDa
Observed MW: 65 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Cytochrome B-245 Heavy Chain (CYBB) Antibody

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