Cytochrome P450 11A1 (CYP11A1) Antibody

Catalogue No: abx001432
Price: £120.00
(Size: 20 µl)
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CYP11A1 Antibody is a Rabbit Polyclonal antibody against CYP11A1. The formation of biologically active steroid hormones is significantly influenced by the motrochondrial cytochrome P450 enzyme, chrolesterol side-chain cleavage. CYP11A1 functions in catalyzing the first step of steroid biosynthesis under modulation of cAMP.It ia also known as cytochrome P450C11A1, cytochrome P450scc and cytochrome P450, subfamily XIA. Expression of CYP11A1 has been a useful tool for monitoring the differentiation state of cells from varius endocrine tissues. Identification of CYP11A1 expression by 13363-1-AP detected a ~45kd band in human placenta, with respect to the reported band at 49-52kd by Roby, et al and Durkee, et al.

Target CYP11A1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/20 - 1/50, IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CYP11A1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P05108 (UniProt, ExPASy)
UniProt Secondary AC A8K8D5, B3KPU8, G3XAD7, Q15081, Q16805, Q8N1A7
UniProt Entry Name CP11A_HUMAN
Gene Symbol CYP11A1
GeneID 1583
KEGG hsa:1583
String 9606.ENSP00000268053
Molecular Weight Calculated MW: 42 kDa, 60 kDa
Observed MW: 45 kDa, 50 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on CYP11A1

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