Cytochrome P450 11A1 (CYP11A1) Antibody

CYP11A1 Antibody is a Rabbit Polyclonal antibody against CYP11A1. The formation of biologically active steroid hormones is significantly influenced by the motrochondrial cytochrome P450 enzyme, chrolesterol side-chain cleavage. CYP11A1 functions in catalyzing the first step of steroid biosynthesis under modulation of cAMP.It ia also known as cytochrome P450C11A1, cytochrome P450scc and cytochrome P450, subfamily XIA. Expression of CYP11A1 has been a useful tool for monitoring the differentiation state of cells from varius endocrine tissues. Identification of CYP11A1 expression by 13363-1-AP detected a ~45kd band in human placenta, with respect to the reported band at 49-52kd by Roby, et al and Durkee, et al.

Target	Cytochrome P450 11A1 (CYP11A1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of CYP11A1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P05108 (UniProt, ExPASy)
UniProt Secondary AC	A8K8D5, B3KPU8, G3XAD7, Q15081, Q16805, Q8N1A7
UniProt Entry Name	CP11A_HUMAN
Gene Symbol	CYP11A1
GeneID	1583
NCBI Accession	NP_000772.2
KEGG	hsa:1583
String	9606.ENSP00000268053
Molecular Weight	Calculated MW: 60 kDa Observed MW: 50 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cytochrome P450 11A1 (CYP11A1)

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