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Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1) Antibody

Catalogue No: abx001208
Price: £120.00
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Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1) Antibody

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CYP17A1 Antibody is a Rabbit Polyclonal antibody against CYP17A1. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008].

Target CYP17A1
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CYP17A1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P05093 (UniProt, ExPASy)
UniProt Secondary AC Q5TZV7
UniProt Entry Name CP17A_HUMAN
Gene Symbol CYP17A1
GeneID 1586
KEGG hsa:1586
String 9606.ENSP00000358903
Molecular Weight Calculated MW: 57 kDa
Observed MW: 50 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1) Antibody

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