Aromatase (CYP19A1) Antibody

REQUEST MORE INFO
Catalogue No: abx001773
Price: US$203.00
(Size: 20 µl)

Click on the image to see the image legend

Available Options

* Size:




Add to Shopping Cart Buy It Now GET A QUOTE

Documents

Datasheet SDS
CYP19A1 Antibody is a Rabbit Polyclonal antibody against CYP19A1. CYP19A1(Cytochrome P450 19A1) is also named as ARO1(aromatase), CYAR, CYP19, estrogen synthase and belongs to the cytochrome P450 family. It is a terminal enzyme which transforms irreversibly androgens into estrogens and it is present in the endoplasmic reticulum of numerous tissues(PMID:16406261). The gene encodes a protein with the molecular weight between 46 kDa and 69 kDa(PMID:8129748) and the protein can be glycosylated, but the level of glycosylation does not seem to be essential for CYP19A1 activity(PMID:12606587). Brain aromatase may be neuroprotective by increasing the local estrogen levels in injured neurons so that genetic variation in the brain aromatase gene may modify the risk for AD(PMID:16767510). This antibody is specific to CYP19A1.

Target Aromatase (CYP19A1)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human Aromatase (CYP19A1).
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P11511 (UniProt, ExPASy)
UniProt Secondary AC Q16731, Q3B764, Q58FA0, Q8IYJ7
UniProt Entry Name CP19A_HUMAN
Gene Symbol CYP19A1
GeneID 1588
NCBI Accession NP_000094.2
KEGG hsa:1588
String 9606.ENSP00000379683
Molecular Weight Calculated MW: 58 kDa
Observed MW: 53 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Aromatase (CYP19A1)


Write a review