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Cytochrome P450 2C9 (CYP2C9) Antibody
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Catalogue No: abx004750
Price:
US$217.50
(Size: 20 µl)
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CYP2C9 Antibody is a Rabbit Polyclonal antibody against CYP2C9. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.
Research Articles on Cytochrome P450 2C9 (CYP2C9)
| Target | Cytochrome P450 2C9 (CYP2C9) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 211-490 of human CYP2C9. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P11712 (UniProt, ExPASy) |
| UniProt Secondary AC | P11713, Q16756, Q16872, Q5VX92, Q6IRV8, Q8WW80 |
| Gene Symbol | CYP2C9 |
| GeneID | 1559 |
| OMIM | 601130 |
| NCBI Accession | NP_000762.2 |
| HGNC | 2623 |
| KEGG | hsa:1559 |
| Ensembl | ENSG00000138109 |
| String | 9606.ENSP00000260682 |
| Molecular Weight | Calculated MW: 56 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |