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Cytochrome P450 2E1 (CYP2E1) Antibody

Catalogue No: abx001772
Price: £120.00
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Cytochrome P450 2E1 (CYP2E1) Antibody Cytochrome P450 2E1 (CYP2E1) Antibody Cytochrome P450 2E1 (CYP2E1) Antibody

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CYP2E1 Antibody is a Rabbit Polyclonal antibody against CYP2E1. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. [provided by RefSeq, Jul 2008].

Target CYP2E1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100, IF/ICC: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CYP2E1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P05181 (UniProt, ExPASy)
UniProt Secondary AC Q5VZD5, Q6NWT9, Q9UK47
UniProt Entry Name CP2E1_HUMAN
Gene Symbol CYP2E1
GeneID 1571
OMIM 124040
HGNC 2631
KEGG hsa:1571
Ensembl ENSG00000130649
String 9606.ENSP00000440689
Molecular Weight Calculated MW: 56 kDa
Observed MW: 55 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Cytochrome P450 2E1 (CYP2E1) Antibody

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