Cysteine Rich Protein, Angiogenic Inducer 61 (CYR61) Antibody
REQUEST MORE INFO
Catalogue No: abx001028
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
(
Click on the image to see the image legend
Add to Cart
Buy It Now
GET A QUOTE
Documents
Datasheet SDS
CYR61 Antibody is a Rabbit Polyclonal antibody against CYR61. Cyr61 is a secreted heparin binding protein, encoded by a growth factor-inducible immediate-early gene, that associates with the extracellular matrix and connective tissue. Cyr61 is a member of a distinct family of angiogenic and vasculogenic regulators designated CCN proteins, which includes connective tissue growth factor (CTGF) and the mouse Cyr61 homolog, Fisp12. As an angiogenic inducer, Cyr61 binds to the cell surface receptor Integrin aV/b3, where it then stimulates cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Expression of Cyr61 is elevated during vessel growth, wound healing and chondrocyte differentiation. Cyr61 is also detected in a wide variety of tumors as it induces tumor growth and functions as a marker of tumor progression.
Research Articles on Cysteine Rich Protein, Angiogenic Inducer 61 (CYR61)
| Target | Cysteine Rich Protein, Angiogenic Inducer 61 (CYR61) |
| Research Area | Tumor Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to human CYR61 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O00622 (UniProt, ExPASy) |
| UniProt Secondary AC | O14934, O43775, Q9BZL7 |
| UniProt Entry Name | CCN1_HUMAN |
| Gene Symbol | CCN1 |
| GeneID | 3491 |
| NCBI Accession | NP_001545.2 |
| KEGG | hsa:3491 |
| String | 9606.ENSP00000398736 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
