Cysteinyl Leukotriene Receptor 1 (CYSLTR1) Antibody
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Catalogue No: abx028326
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
Research Articles on Cysteinyl Leukotriene Receptor 1 (CYSLTR1)
| Target | Cysteinyl Leukotriene Receptor 1 (CYSLTR1) |
| Research Area | Metabolism, Infection Immunity, Endocrinology, Hormone Metabolism, Bone Metabolism, Rheumatology |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 144-172 amino acids from the Central region of human CYSLTR1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9Y271 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R954, D3DTE4, Q5JS94, Q8IV19 |
| UniProt Entry Name | CLTR1_HUMAN |
| Gene Symbol | CYSLTR1 |
| String | 9606.ENSP00000478492 |
| Molecular Weight | Calculated MW: 38.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |