Disheveled-Associated Activator of Morphogenesis 1 (DAAM1) Antibody
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Catalogue No: abx031655
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton. Recent evidence suggests a role for the Formin homology (FH) proteins in these processes. DAAM1 contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by DAAM1, which is thought to function as a scaffolding protein.
Research Articles on Disheveled-Associated Activator of Morphogenesis 1 (DAAM1)
| Target | Disheveled-Associated Activator of Morphogenesis 1 (DAAM1) |
| Research Area | Immunology |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 45-74 amino acids from the N-terminal region of human DAAM1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9Y4D1 (UniProt, ExPASy) |
| UniProt Secondary AC | Q86U34, Q8N1Z8, Q8TB39 |
| UniProt Entry Name | DAAM1_HUMAN |
| Gene Symbol | DAAM1 |
| String | 9606.ENSP00000378557 |
| Molecular Weight | Calculated MW: 123 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse DAAM1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |