Acyl-CoA-Binding Protein (DBI) Antibody

DBI Antibody is a Rabbit Polyclonal antibody against DBI. This gene encodes Acyl-CoA-Binding Protein, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Acyl-CoA-Binding Protein is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

Target	Acyl-CoA-Binding Protein (DBI)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IP: 0.5-4 µg/200-400 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-104 of human DBI.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P07108 (UniProt, ExPASy)
UniProt Entry Name	ACBP_HUMAN
Gene Symbol	DBI
GeneID	1622
NCBI Accession	NP_001171513.1
KEGG	hsa:1622
String	9606.ENSP00000439012
Molecular Weight	Calculated MW: 10 kDa Observed MW: 12 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	2.30 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Acyl-CoA-Binding Protein (DBI)

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