Acyl-CoA-Binding Protein (DBI) Antibody
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Catalogue No: abx004111
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US$217.50
(Size: 20 µl)
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(![Western blot analysis of lysates from wild type (WT) and DBI knockout (KO) 293T cells, using [KO Validated] DBI Antibody at 1/1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Exposure time: 1s.](https://www.abbexa.com/image/cache/data/products/18B/abx004111_1-500x500.jpg "Acyl-CoA-Binding Protein (DBI) Antibody")
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Datasheet SDS
DBI Antibody is a Rabbit Polyclonal antibody against DBI. This gene encodes Acyl-CoA-Binding Protein, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Acyl-CoA-Binding Protein is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.
Research Articles on Acyl-CoA-Binding Protein (DBI)
| Target | Acyl-CoA-Binding Protein (DBI) |
| Research Area | Metabolism |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IP |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to DBI. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P07108 (UniProt, ExPASy) |
| UniProt Entry Name | ACBP_HUMAN |
| Gene Symbol | DBI |
| GeneID | 1622 |
| NCBI Accession | NP_001171513.1 |
| KEGG | hsa:1622 |
| String | 9606.ENSP00000439012 |
| Molecular Weight | Calculated MW: 10 kDa Observed MW: 12 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 2.30 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |