Doublecortin-Like And CAM Kinase-Like 1 (DCAMKL1) Antibody
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Catalogue No: abx033240
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US$326.25
(Size: 50 µl)
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Datasheet SDS
Doublecortin-like kinase (DCAMKL1) (Ser/Thr protein kinase family) is essential for proper neurogenesis, neuronal migration, and axonal wiring. DCAMKL1 is involved in a calcium-signaling pathway controling neuronal migration in the developing brain, and participates in functions of the mature nervous system. DCAMKL1 protein shares high homology with doublecortin (DCX). DCLK, but not DCX, is highly expressed in regions of active neurogenesis in the neocortex and cerebellum. DCAMKL1 controls mitotic division by regulating spindle formation and also determines the fate of neural progenitors during cortical neurogenesis.
Research Articles on Doublecortin-Like And CAM Kinase-Like 1 (DCAMKL1)
| Target | Doublecortin-Like And CAM Kinase-Like 1 (DCAMKL1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/8000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 690-720 amino acids from the C-terminal region of human DCAMKL1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O15075 (UniProt, ExPASy) |
| UniProt Secondary AC | B7Z3E9, Q5VZY8, Q5VZZ0, Q5VZZ1 |
| Gene Symbol | DCAMKL1 |
| NCBI Accession | NP_001182344.1 NP_001182345.1 NP_004725.1 |
| Molecular Weight | Calculated MW: 82.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |