Deoxycytidine Kinase (DCK) Antibody

Catalogue No: abx001486
Price: £120.00
(Size: 20 µl)
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DCK Antibody is a Rabbit Polyclonal antibody against DCK. Deoxycytidine kinase (dCK) is required for the phosphorylation of several deoxyribonucleoside analogues that are widely employed as chemotherapeutic agents(PMID:12628850). It is also a key enzyme in the phosphorylation of a variety of antineoplastic and antiviral nucleoside analogs including cytosine arabinoside (araC) and dideoxycytidine (ddCyd); deficiency of deoxycytidine kinase activity mediates resistance to these drugs(PMID:1996353). This protein can exsit as a homodimer(PMID:16421443). This antibody is specific to DCK.

Target DCK
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human DCK.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P27707 (UniProt, ExPASy)
UniProt Secondary AC B2R8V6, Q5TZY7, Q6FI11
UniProt Entry Name DCK_HUMAN
Gene Symbol DCK
GeneID 1633
KEGG hsa:1633
String 9606.ENSP00000286648
Molecular Weight Calculated MW: 30 kDa
Observed MW: 31 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on DCK

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