Dcr-1 Antibody

Dcr-1 Antibody is a Rabbit Polyclonal antibody for the detection of C. elegans Dcr-1.

The Dcr-1 gene encodes a bidentate ribonuclease that is homologous to E. coli RNAse III. Dcr-1 is required both for RNA interference and for synthesis of small developmental RNAs. Dcr-1 interacts in vivo with RDE-4, a double-stranded RNA (dsRNA) binding protein required for RNAi that interacts with trigger dsRNAs and may function to deliver dsRNAs to Dcr-1 for endonucleolytic processing. This antibody is reactive against C. elegans Dcr-1.

Target	Dcr-1
Clonality	Polyclonal
Reactivity	Worm
Tested Applications	ELISA
Host	Rabbit
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1068-1097 amino acids from the Central region of human Dcr-1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P34529 (UniProt, ExPASy)
UniProt Entry Name	DCR1_CAEEL
KEGG	cel:CELE_K12H4.8
String	6239.K12H4.8
Molecular Weight	Calculated MW: 218 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Reacts with C. elegans Dcr-1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Dcr-1

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